Hospital rankings

Hospitals in South Carolina with the lowest C. diff infections

48 South Carolina hospitals ranked by C. diff infections in the 2026 Medicare (CMS) data. Leading: Pelham Medical Center, Prisma Health Patewood Hospital, Roper St Francis Hospital-Berkeley Inc. Filter by type, ownership and size, choose the measures you care about, and sort by any column.

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48 hospitals ranked in South Carolina by c. diff infections; 18 more match but have no reported value.

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Hospital rankings, page 1 of 1. Columns can be sorted.
#	Hospital	C. diff infectionslower is better	Serious complicationslower is better	Central line bloodstream infectionslower is better	Catheter-associated urinary tract infectionslower is better	Surgical site infections (colon)lower is better	Surgical site infections (hysterectomy)lower is better	MRSA bloodstream infectionslower is better	Compare
	National average	1.00	1.00	1.00	1.00	1.00	1.00	1.00
T1	Pelham Medical CenterGreer, SC · Acute care	0.00, 90th percentile	0.92, 67th percentile	0.00, 90th percentile	—	0.42, 69th percentile	—	—	Compare Pelham Medical Center
T1	Prisma Health Patewood HospitalGreenville, SC · Acute care	0.00, 90th percentile	0.93, 63rd percentile	—	—	—	—	—	Compare Prisma Health Patewood Hospital
T1	Roper St Francis Hospital-Berkeley IncSummerville, SC · Acute care	0.00, 90th percentile	0.85, 85th percentile	—	—	—	—	—	Compare Roper St Francis Hospital-Berkeley Inc
T1	Coastal Carolina HospitalHardeeville, SC · Acute care	0.00, 90th percentile	0.93, 63rd percentile	—	—	0.67, 53rd percentile	—	—	Compare Coastal Carolina Hospital
T1	Prisma Health Hillcrest HospitalSimpsonville, SC · Acute care	0.00, 90th percentile	0.98, 41st percentile	—	—	—	—	—	Compare Prisma Health Hillcrest Hospital
T1	Prisma Health Laurens County HospitalClinton, SC · Acute care	0.00, 90th percentile	0.94, 59th percentile	—	—	—	—	0.00, 91st percentile	Compare Prisma Health Laurens County Hospital
T1	Colleton Medical CenterWalterboro, SC · Acute care	0.00, 90th percentile	1.07, 23rd percentile	—	0.00, 88th percentile	—	—	—	Compare Colleton Medical Center
T1	Newberry County Memorial HospitalNewberry, SC · Acute care	0.00, 90th percentile	0.87, 81st percentile	—	—	—	—	—	Compare Newberry County Memorial Hospital
T1	Abbeville Area Medical CenterAbbeville, SC · Critical access	0.00, 90th percentile	—	—	1.36, 6th percentile	—	—	—	Compare Abbeville Area Medical Center
T1	Hampton Regional Medical CenterVarnville, SC · Acute care	0.00, 90th percentile	0.98, 41st percentile	—	—	—	—	—	Compare Hampton Regional Medical Center
11	McLeod Loris HospitalLoris, SC · Acute care	0.08, 76th percentile	0.78, 95th percentile	0.38, 60th percentile	1.21, 8th percentile	0.90, 37th percentile	—	0.31, 74th percentile	Compare McLeod Loris Hospital
12	Prisma Health BaptistColumbia, SC · Acute care	0.09, 76th percentile	0.72, 98th percentile	0.58, 41st percentile	0.44, 46th percentile	1.72, 10th percentile	3.86, 2nd percentile	0.25, 77th percentile	Compare Prisma Health Baptist
13	Piedmont Medical CenterRock Hill, SC · Acute care	0.10, 74th percentile	1.29, 7th percentile	0.32, 65th percentile	0.19, 68th percentile	0.26, 77th percentile	—	0.97, 23rd percentile	Compare Piedmont Medical Center
14	Grand Strand Regional Medical CenterMyrtle Beach, SC · Acute care	0.12, 73rd percentile	0.94, 59th percentile	0.73, 30th percentile	0.57, 34th percentile	1.28, 21st percentile	—	0.28, 75th percentile	Compare Grand Strand Regional Medical Center
15	Bon Secours-St Francis Xavier HospitalCharleston, SC · Acute care	0.13, 72nd percentile	0.80, 93rd percentile	0.00, 90th percentile	1.25, 7th percentile	0.33, 74th percentile	0.70, 58th percentile	1.25, 12th percentile	Compare Bon Secours-St Francis Xavier Hospital
16	Prisma Health Tuomey HospitalSumter, SC · Acute care	0.13, 71st percentile	0.86, 83rd percentile	0.45, 53rd percentile	0.56, 35th percentile	0.00, 91st percentile	—	0.00, 91st percentile	Compare Prisma Health Tuomey Hospital
17	Prisma Health Oconee Memorial HospitalSeneca, SC · Acute care	0.16, 68th percentile	1.01, 33rd percentile	0.00, 90th percentile	1.02, 11th percentile	2.77, 1st percentile	—	0.00, 91st percentile	Compare Prisma Health Oconee Memorial Hospital
18	Self Regional HealthcareGreenwood, SC · Acute care	0.18, 65th percentile	0.98, 41st percentile	0.77, 28th percentile	0.18, 69th percentile	0.54, 61st percentile	—	0.28, 75th percentile	Compare Self Regional Healthcare
19	Aiken Regional Medical CenterAiken, SC · Acute care	0.19, 63rd percentile	1.21, 10th percentile	0.25, 70th percentile	0.37, 52nd percentile	1.21, 24th percentile	—	0.54, 55th percentile	Compare Aiken Regional Medical Center
20	Anmed HealthAnderson, SC · Acute care	0.23, 58th percentile	0.77, 95th percentile	0.90, 20th percentile	0.78, 21st percentile	0.84, 41st percentile	0.00, 89th percentile	0.75, 37th percentile	Compare Anmed Health
T21	Prisma Health Baptist ParkridgeColumbia, SC · Acute care	0.24, 56th percentile	0.80, 93rd percentile	0.73, 30th percentile	—	—	—	0.00, 91st percentile	Compare Prisma Health Baptist Parkridge
T21	St Francis-DowntownGreenville, SC · Acute care	0.24, 56th percentile	0.80, 93rd percentile	0.12, 78th percentile	0.30, 60th percentile	1.61, 12th percentile	—	1.21, 14th percentile	Compare St Francis-Downtown
23	Carolina Pines Regional Medical CenterHartsville, SC · Acute care	0.24, 56th percentile	1.12, 17th percentile	—	—	—	—	—	Compare Carolina Pines Regional Medical Center
T24	Prisma Health Greenville Memorial HospitalGreenville, SC · Acute care	0.25, 54th percentile	0.93, 63rd percentile	0.79, 26th percentile	0.53, 37th percentile	1.62, 11th percentile	1.15, 36th percentile	0.43, 65th percentile	Compare Prisma Health Greenville Memorial Hospital
T24	Prisma Health Richland HospitalColumbia, SC · Acute care	0.25, 54th percentile	1.15, 14th percentile	0.56, 43rd percentile	0.67, 26th percentile	2.51, 2nd percentile	0.75, 55th percentile	0.71, 40th percentile	Compare Prisma Health Richland Hospital
26	McLeod Health ClarendonManning, SC · Acute care	0.26, 53rd percentile	0.94, 59th percentile	—	—	—	—	—	Compare McLeod Health Clarendon
27	Tidelands Georgetown Memorial HospitalGeorgetown, SC · Acute care	0.26, 53rd percentile	0.92, 67th percentile	—	—	—	—	1.43, 9th percentile	Compare Tidelands Georgetown Memorial Hospital
28	Spartanburg Medical CenterSpartanburg, SC · Acute care	0.27, 51st percentile	0.79, 94th percentile	0.13, 77th percentile	0.35, 55th percentile	0.64, 55th percentile	—	0.59, 51st percentile	Compare Spartanburg Medical Center
29	Cherokee Medical CenterGaffney, SC · Acute care	0.28, 49th percentile	0.96, 51st percentile	—	—	—	—	—	Compare Cherokee Medical Center
30	Trident Medical CenterCharleston, SC · Acute care	0.29, 49th percentile	0.81, 92nd percentile	0.70, 32nd percentile	0.80, 20th percentile	1.00, 31st percentile	0.97, 41st percentile	0.40, 68th percentile	Compare Trident Medical Center
31	Lexington Medical CenterWest Columbia, SC · Acute care	0.30, 48th percentile	0.88, 78th percentile	0.58, 42nd percentile	0.43, 47th percentile	0.91, 36th percentile	0.63, 64th percentile	0.00, 91st percentile	Compare Lexington Medical Center
T32	Roper HospitalCharleston, SC · Acute care	0.30, 47th percentile	0.75, 97th percentile	0.84, 24th percentile	0.22, 66th percentile	0.38, 71st percentile	1.65, 22nd percentile	2.20, 2nd percentile	Compare Roper Hospital
T32	Novant Health Hilton Head Medical CenterHilton Head Island, SC · Acute care	0.30, 47th percentile	0.88, 78th percentile	—	—	1.08, 28th percentile	—	—	Compare Novant Health Hilton Head Medical Center
34	Conway Medical CenterConway, SC · Acute care	0.32, 45th percentile	1.10, 19th percentile	0.00, 90th percentile	0.38, 52nd percentile	1.61, 12th percentile	—	0.89, 27th percentile	Compare Conway Medical Center
35	MUSC Health Lancaster Medical CenterLancaster, SC · Acute care	0.33, 43rd percentile	0.83, 89th percentile	0.00, 90th percentile	0.36, 54th percentile	0.00, 91st percentile	—	0.72, 39th percentile	Compare MUSC Health Lancaster Medical Center
36	MUSC Health Florence Medical CenterFlorence, SC · Acute care	0.35, 40th percentile	1.05, 26th percentile	1.52, 6th percentile	0.82, 19th percentile	0.51, 64th percentile	—	0.90, 27th percentile	Compare MUSC Health Florence Medical Center
37	Novant Health East Cooper Medical CenterMount Pleasant, SC · Acute care	0.35, 40th percentile	1.00, 35th percentile	—	—	—	—	—	Compare Novant Health East Cooper Medical Center
38	Tidelands Waccamaw Community HospitalMurrells Inlet, SC · Acute care	0.38, 36th percentile	0.98, 41st percentile	0.00, 90th percentile	0.00, 88th percentile	0.42, 69th percentile	—	0.00, 91st percentile	Compare Tidelands Waccamaw Community Hospital
39	Prisma Health Greer Memorial HospitalSpartanburg, SC · Acute care	0.39, 35th percentile	0.97, 46th percentile	—	1.29, 6th percentile	—	—	0.69, 42nd percentile	Compare Prisma Health Greer Memorial Hospital
40	MUSC Health Columbia Medical Center DowntownColumbia, SC · Acute care	0.39, 35th percentile	1.27, 7th percentile	0.35, 62nd percentile	0.90, 15th percentile	0.24, 78th percentile	—	0.91, 26th percentile	Compare MUSC Health Columbia Medical Center Downtown
41	McLeod Regional Medical Center-Pee DeeFlorence, SC · Acute care	0.49, 25th percentile	1.07, 23rd percentile	0.56, 44th percentile	0.41, 49th percentile	1.74, 9th percentile	—	0.81, 33rd percentile	Compare McLeod Regional Medical Center-Pee Dee
42	MUSC Medical CenterCharleston, SC · Acute care	0.52, 23rd percentile	1.48, 3rd percentile	0.84, 23rd percentile	0.78, 20th percentile	1.47, 15th percentile	1.62, 24th percentile	0.94, 24th percentile	Compare MUSC Medical Center
43	Prisma Health Baptist Easley HospitalEasley, SC · Acute care	0.54, 21st percentile	0.99, 37th percentile	0.70, 32nd percentile	0.60, 32nd percentile	—	—	0.00, 91st percentile	Compare Prisma Health Baptist Easley Hospital
44	KershawHealthCamden, SC · Acute care	0.66, 15th percentile	1.11, 18th percentile	—	0.00, 88th percentile	2.97, 0th percentile	—	—	Compare KershawHealth
45	Mount Pleasant HospitalMount Pleasant, SC · Acute care	0.70, 13th percentile	0.90, 73rd percentile	—	—	0.22, 79th percentile	—	—	Compare Mount Pleasant Hospital
46	McLeod Health CherawCheraw, SC · Acute care	0.81, 9th percentile	0.94, 59th percentile	—	0.94, 13th percentile	—	—	—	Compare McLeod Health Cheraw
47	Beaufort County Memorial HospitalBeaufort, SC · Acute care	0.83, 9th percentile	1.07, 23rd percentile	1.35, 7th percentile	0.40, 50th percentile	1.68, 10th percentile	—	0.00, 91st percentile	Compare Beaufort County Memorial Hospital
48	McLeod Medical Center - DillonDillon, SC · Acute care	1.31, 3rd percentile	1.00, 35th percentile	—	—	—	—	—	Compare McLeod Medical Center - Dillon

About these rankings

Rankings use the 2026 release of CMS Care Compare data. Hospitals share a rank (“T”) when their values are equal, and only hospitals with a reported value for the sorted measure are ranked. Shading compares each value with every hospital in the country, so it doesn’t change with your filters. Small differences are often not statistically meaningful; use the methodology and glossary for context.

C. diff infections: Clostridium difficile (C. diff) intestinal infections (standardized infection ratio; 1.0 = national baseline).
Serious complications: Patient safety and adverse events composite (PSI 90; 1.0 = national value).
Central line bloodstream infections: Central line-associated bloodstream infections (CLABSI) in ICUs and select wards (standardized infection ratio; 1.0 = national baseline).
Catheter-associated urinary tract infections: Catheter-associated urinary tract infections (CAUTI) in ICUs and select wards (standardized infection ratio; 1.0 = national baseline).
Surgical site infections (colon): Surgical site infections from colon surgery (standardized infection ratio; 1.0 = national baseline).
Surgical site infections (hysterectomy): Surgical site infections from abdominal hysterectomy (standardized infection ratio; 1.0 = national baseline).
MRSA bloodstream infections: Methicillin-resistant Staphylococcus aureus (MRSA) blood laboratory-identified events (standardized infection ratio; 1.0 = national baseline).