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Best hospitals in Sioux Falls, South Dakota

CMS lists 6 active hospitals in Sioux Falls, South Dakota: 4 acute care hospitals, 1 VA hospital and 1 children's hospital. 4 offer emergency services. The highest CMS overall rating here is 5 stars, held by Sanford USDMedical Center, Sioux Falls VA Medical Center and Avera Heart Hospital Of South Dakota.

Compare the top 3
Hospitals
6
With a CMS star rating
4
Rated 5 stars
3
Emergency services
4
Beds
1,424

Best hospitals in Sioux Falls, South Dakota, by measure

The best result among Sioux Falls, South Dakota hospitals that report each measure, from the latest CMS data. Small differences between hospitals are often not statistically meaningful.

MeasureBest in Sioux FallsResultNational
Overall star ratingHigher is better · 4 hospitals reporting · Statewide rankingAvera Heart Hospital Of South Dakota, Sanford USDMedical Center, Sioux Falls VA Medical Center (tied)5—
Patient survey star ratingHigher is better · 5 hospitals reporting · Statewide rankingSioux Falls Specialty Hospital, Sioux Falls VA Medical Center (tied)53.3
Heart attack death rateLower is better · 3 hospitals reporting · Statewide rankingAvera Heart Hospital Of South Dakota, Sanford USDMedical Center (tied)10.9%11.9%
Heart failure death rateLower is better · 4 hospitals reporting · Statewide rankingAvera Heart Hospital Of South Dakota10.6%11.1%
Stroke death rateLower is better · 2 hospitals reporting · Statewide rankingSanford USDMedical Center10.6%11.9%
Hospital-wide readmission rateLower is better · 5 hospitals reporting · Statewide rankingSioux Falls VA Medical Center13.6%15.0%
Serious complicationsLower is better · 5 hospitals reporting · Statewide rankingSanford USDMedical Center0.641.00
Central line bloodstream infectionsLower is better · 2 hospitals reporting · Statewide rankingSanford USDMedical Center0.261.00
Time in emergency departmentLower is better · 3 hospitals reporting · Statewide rankingAvera Heart Hospital Of South Dakota110 min162 min

All hospitals in Sioux Falls, South Dakota

Sorted by CMS overall star rating, then size. CMS data as of Sep 30, 2026.

HospitalCMS overall ratingPatient survey ratingEmergency servicesBeds
Sanford USDMedical CenterAcute care hospitalYes545Compare
Sioux Falls VA Medical CenterVA hospitalYes270Compare
Avera Heart Hospital Of South DakotaAcute care hospitalYes53Compare
Avera McKennan Hospital & University Health CenterAcute care hospitalYes505Compare
Sioux Falls Specialty HospitalAcute care hospitalNot ratedNo33Compare
LifescapeChildren's hospitalNot ratedNot ratedNo18Compare