| Charleston Va Medical CenterVA hospital · Charleston | ★★★★★ | ★★★★★ | Yes | 500 | Compare Charleston Va Medical Center |
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| Columbia Sc Va Medical CenterVA hospital · Columbia | ★★★★★ | ★★★★★ | Yes | 410 | Compare Columbia Sc Va Medical Center |
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| Mount Pleasant HospitalAcute care hospital · Mount Pleasant | ★★★★★ | ★★★★★ | Yes | 85 | Compare Mount Pleasant Hospital |
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| Prisma Health Greer Memorial HospitalAcute care hospital · Spartanburg | ★★★★★ | ★★★★★ | Yes | 82 | Compare Prisma Health Greer Memorial Hospital |
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| Prisma Health Patewood HospitalAcute care hospital · Greenville | ★★★★★ | ★★★★★ | No | 72 | Compare Prisma Health Patewood Hospital |
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| Roper St Francis Hospital-Berkeley IncAcute care hospital · Summerville | ★★★★★ | ★★★★★ | Yes | 50 | Compare Roper St Francis Hospital-Berkeley Inc |
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| Pelham Medical CenterAcute care hospital · Greer | ★★★★★ | ★★★★★ | Yes | 48 | Compare Pelham Medical Center |
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| Prisma Health Greenville Memorial HospitalAcute care hospital · Greenville | ★★★★★ | ★★★★★ | No | 845 | Compare Prisma Health Greenville Memorial Hospital |
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| Anmed HealthAcute care hospital · Anderson | ★★★★★ | ★★★★★ | Yes | 533 | Compare Anmed Health |
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| Roper HospitalAcute care hospital · Charleston | ★★★★★ | ★★★★★ | Yes | 368 | Compare Roper Hospital |
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| Self Regional HealthcareAcute care hospital · Greenwood | ★★★★★ | ★★★★★ | Yes | 358 | Compare Self Regional Healthcare |
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| Prisma Health BaptistAcute care hospital · Columbia | ★★★★★ | ★★★★★ | Yes | 352 | Compare Prisma Health Baptist |
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| St Francis-DowntownAcute care hospital · Greenville | ★★★★★ | ★★★★★ | Yes | 245 | Compare St Francis-Downtown |
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| MUSC Health Lancaster Medical CenterAcute care hospital · Lancaster | ★★★★★ | ★★★★★ | Yes | 217 | Compare MUSC Health Lancaster Medical Center |
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| Beaufort County Memorial HospitalAcute care hospital · Beaufort | ★★★★★ | ★★★★★ | Yes | 197 | Compare Beaufort County Memorial Hospital |
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| Prisma Health Oconee Memorial HospitalAcute care hospital · Seneca | ★★★★★ | ★★★★★ | Yes | 169 | Compare Prisma Health Oconee Memorial Hospital |
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| Novant Health East Cooper Medical CenterAcute care hospital · Mount Pleasant | ★★★★★ | ★★★★★ | Yes | 140 | Compare Novant Health East Cooper Medical Center |
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| Tidelands Waccamaw Community HospitalAcute care hospital · Murrells Inlet | ★★★★★ | ★★★★★ | Yes | 124 | Compare Tidelands Waccamaw Community Hospital |
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| McLeod Loris HospitalAcute care hospital · Loris | ★★★★★ | ★★★★★ | No | 105 | Compare McLeod Loris Hospital |
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| Prisma Health Laurens County HospitalAcute care hospital · Clinton | ★★★★★ | ★★★★★ | Yes | 76 | Compare Prisma Health Laurens County Hospital |
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| Prisma Health Hillcrest HospitalAcute care hospital · Simpsonville | ★★★★★ | ★★★★★ | Yes | 43 | Compare Prisma Health Hillcrest Hospital |
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| Coastal Carolina HospitalAcute care hospital · Hardeeville | ★★★★★ | ★★★★★ | Yes | 41 | Compare Coastal Carolina Hospital |
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| Prisma Health Baptist Easley HospitalAcute care hospital · Easley | ★★★★★ | ★★★★★ | Yes | — | Compare Prisma Health Baptist Easley Hospital |
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| Prisma Health Baptist ParkridgeAcute care hospital · Columbia | ★★★★★ | ★★★★★ | Yes | — | Compare Prisma Health Baptist Parkridge |
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| Prisma Health Richland HospitalAcute care hospital · Columbia | ★★★★★ | ★★★★★ | Yes | 649 | Compare Prisma Health Richland Hospital |
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| Trident Medical CenterAcute care hospital · Charleston | ★★★★★ | ★★★★★ | Yes | 497 | Compare Trident Medical Center |
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| McLeod Regional Medical Center-Pee DeeAcute care hospital · Florence | ★★★★★ | ★★★★★ | Yes | 461 | Compare McLeod Regional Medical Center-Pee Dee |
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| Lexington Medical CenterAcute care hospital · West Columbia | ★★★★★ | ★★★★★ | Yes | 460 | Compare Lexington Medical Center |
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| MUSC Health Florence Medical CenterAcute care hospital · Florence | ★★★★★ | ★★★★★ | Yes | 420 | Compare MUSC Health Florence Medical Center |
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| Prisma Health Tuomey HospitalAcute care hospital · Sumter | ★★★★★ | ★★★★★ | Yes | 283 | Compare Prisma Health Tuomey Hospital |
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| MUSC Health Columbia Medical Center DowntownAcute care hospital · Columbia | ★★★★★ | ★★★★★ | Yes | 258 | Compare MUSC Health Columbia Medical Center Downtown |
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| Bon Secours-St Francis Xavier HospitalAcute care hospital · Charleston | ★★★★★ | ★★★★★ | Yes | 204 | Compare Bon Secours-St Francis Xavier Hospital |
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| Colleton Medical CenterAcute care hospital · Walterboro | ★★★★★ | ★★★★★ | Yes | 135 | Compare Colleton Medical Center |
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| MUSC Health Marion Medical CenterAcute care hospital · Mullins | ★★★★★ | ★★★★★ | Yes | 124 | Compare MUSC Health Marion Medical Center |
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| KershawHealthAcute care hospital · Camden | ★★★★★ | ★★★★★ | Yes | 119 | Compare KershawHealth |
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| McLeod Medical Center - DillonAcute care hospital · Dillon | ★★★★★ | ★★★★★ | Yes | 92 | Compare McLeod Medical Center - Dillon |
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| Newberry County Memorial HospitalAcute care hospital · Newberry | ★★★★★ | ★★★★★ | Yes | 90 | Compare Newberry County Memorial Hospital |
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| McLeod Health ClarendonAcute care hospital · Manning | ★★★★★ | ★★★★★ | Yes | 81 | Compare McLeod Health Clarendon |
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| McLeod Health CherawAcute care hospital · Cheraw | ★★★★★ | ★★★★★ | Yes | 59 | Compare McLeod Health Cheraw |
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| Spartanburg Medical CenterAcute care hospital · Spartanburg | ★★★★★ | ★★★★★ | Yes | 747 | Compare Spartanburg Medical Center |
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| MUSC Medical CenterAcute care hospital · Charleston | ★★★★★ | ★★★★★ | Yes | 713 | Compare MUSC Medical Center |
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| Grand Strand Regional Medical CenterAcute care hospital · Myrtle Beach | ★★★★★ | ★★★★★ | Yes | 369 | Compare Grand Strand Regional Medical Center |
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| Piedmont Medical CenterAcute care hospital · Rock Hill | ★★★★★ | ★★★★★ | Yes | 288 | Compare Piedmont Medical Center |
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| Aiken Regional Medical CenterAcute care hospital · Aiken | ★★★★★ | ★★★★★ | Yes | 273 | Compare Aiken Regional Medical Center |
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| Conway Medical CenterAcute care hospital · Conway | ★★★★★ | ★★★★★ | Yes | 210 | Compare Conway Medical Center |
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| Tidelands Georgetown Memorial HospitalAcute care hospital · Georgetown | ★★★★★ | ★★★★★ | Yes | 131 | Compare Tidelands Georgetown Memorial Hospital |
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| Cherokee Medical CenterAcute care hospital · Gaffney | ★★★★★ | ★★★★★ | Yes | 125 | Compare Cherokee Medical Center |
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| Carolina Pines Regional Medical CenterAcute care hospital · Hartsville | ★★★★★ | ★★★★★ | Yes | 116 | Compare Carolina Pines Regional Medical Center |
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| Novant Health Hilton Head Medical CenterAcute care hospital · Hilton Head Island | ★★★★★ | ★★★★★ | Yes | 93 | Compare Novant Health Hilton Head Medical Center |
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| G Werber Bryan Psych HospitalPsychiatric hospital · Columbia | Not rated | Not rated | No | 543 | Compare G Werber Bryan Psych Hospital |
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| NH BeaufortMilitary hospital · Beaufort | Not rated | Not rated | No | 421 | Compare NH Beaufort |
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| Patrick B Harris Psychiatric HospitalPsychiatric hospital · Anderson | Not rated | Not rated | No | 200 | Compare Patrick B Harris Psychiatric Hospital |
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| Union Medical CenterAcute care hospital · Union | Not rated | Not rated | Yes | 143 | Compare Union Medical Center |
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| Carolina Center For Behavioral Health,ThePsychiatric hospital · Greer | Not rated | Not rated | No | 138 | Compare Carolina Center For Behavioral Health,The |
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| Three Rivers Behavioral HealthPsychiatric hospital · West Columbia | Not rated | Not rated | No | 122 | Compare Three Rivers Behavioral Health |
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| Palmetto Lowcountry Behavioral HealthPsychiatric hospital · Charleston | Not rated | Not rated | No | 108 | Compare Palmetto Lowcountry Behavioral Health |
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| Lighthouse Behavioral Health HospitalPsychiatric hospital · Conway | Not rated | Not rated | Yes | 105 | Compare Lighthouse Behavioral Health Hospital |
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| MUSC Health Chester Medical CenterAcute care hospital · Chester | Not rated | ★★★★★ | Yes | 82 | Compare MUSC Health Chester Medical Center |
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| Springbrook Behavioral Health SystemPsychiatric hospital · Travelers Rest | Not rated | Not rated | No | 62 | Compare Springbrook Behavioral Health System |
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| Cannon Memorial HospitalAcute care hospital · Pickens | Not rated | Not rated | Yes | 55 | Compare Cannon Memorial Hospital |
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| Shriners Hospitals For ChildrenChildren's hospital · Greenville | Not rated | Not rated | No | 50 | Compare Shriners Hospitals For Children |
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| Rebound Behavioral HealthPsychiatric hospital · Lancaster | Not rated | Not rated | Yes | 42 | Compare Rebound Behavioral Health |
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| Hampton Regional Medical CenterAcute care hospital · Varnville | Not rated | Not rated | Yes | 32 | Compare Hampton Regional Medical Center |
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| Abbeville Area Medical CenterCritical access hospital · Abbeville | Not rated | Not rated | Yes | 25 | Compare Abbeville Area Medical Center |
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| Allendale County HospitalCritical access hospital · Fairfax | Not rated | Not rated | Yes | 25 | Compare Allendale County Hospital |
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| Edgefield County Healthcare An Affiliate Of Self RCritical access hospital · Edgefield | Not rated | Not rated | Yes | 25 | Compare Edgefield County Healthcare An Affiliate Of Self R |
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